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Monday, October 12, 2009
Health Headlines - October 13
FDA Considers New Insulin Inhaler An insulin inhaler that may offer a more convenient alternative to insulin injections for people with diabetes is being considered for approval by the U.S. Food and Drug Administration. The palm-sized inhaler contains an insulin powder called Afresa, which dissolves in the lungs and then travels the bloodstream, The New York Times reported. The device and powder were developed by California-based MannKind Corporation, which is asking the FDA to approve the system's use in people with type 1 and type 2 diabetes. "The patient's breathing action does the job," Matthew J. Pfeffer, chief financial officer at MannKind, told the Times. "The airflow through the cartridge allows the powder to be inhaled." Patients put insulin doses -- pre-packaged in cartridges -- into the inhaler and turn the mouthpiece to release the insulin. The inhaler uses no electricity or compressed gas. "The patient's breathing action does the job," Pfeffer said. "The airflow through the cartridge allows the powder to be inhaled." An insulin inhaler introduced by Pfizer in 2006 was taken off the market less than two years later due to poor sales. The inhaler was too large and awkward, according to some experts, the Times said. ----- Death Caused By Improper Relenza Use: Drug Maker Inappropriate use of the anti-flu medication Relenza has been linked with at least one death, drug maker GlaxoSmithKline says in a letter sent to doctors. The letter was posted online Friday by the U.S. Food and Drug Administration. The death occurred after the drug was reformulated into a liquid form, an action not recommended by the FDA. Glaxo said Relenza should only be used in the prescribed manner. The letter didn't provide any details about the person who died, the Associated Press reported. Relenza, which comes in powder form to be used with a special inhaler device, is approved by the FDA to treat symptoms of seasonal flu when taken within two days of the start of the flu. Millions of doses of Relenza and Roche's Tamiflu have been stockpiled by the United States, the AP reported. ----- Adult Stem Cells Used to Create Jaw Joint U.S. researchers who used human adult stem cells to create part of a jaw joint in the laboratory said their success could lead to new ways to treat jaw problems and other types of bone disorders. Stem cells taken from bone marrow were seeded into a tissue scaffold, which had been formed into a temporomandibular joint by using digital images from a patient. The cells were infused with the exact amount of nutrients found during natural bone development, BBC News reported. The Columbia University study appears in the journal Proceedings of the National Academy of Sciences. "The availability of personalized bone grafts engineered from the patient's own stem cells would revolutionize the way we currently treat these defects," said lead researcher Dr. Gordana Vunjak-Novakovic, BBC News reported. "We thought the jawbone would be the most rigorous test of our technique; if you can make this, you can make any shape," she noted. ----- 100 Nations to Receive Donated Swine Flu Vaccine: WHO International donations of H1N1 swine flu vaccine will be distributed to about 100 developing countries, perhaps as early as November, according to a World Health Organization official. "The director general of WHO will approve most likely today a list of countries for the donations. The list will include about 100 countries," Marie-Paule Kieny, head of the WHO's vaccine research unit, told journalists, Agence France Presse reported. "We are trying to have the first deliveries in November," she said. The donated swine flu vaccine is from drug companies and a U.S.-led group of wealthy nations that promised to give 10 percent of their vaccine purchases to developing countries, AFP reported. The vaccines will be used to protect about 2 percent of the population in the recipient nations over the next few months. Health-care workers will be given priority, followed by other vulnerable groups, Kieny said. ----- Juggling Benefits Brain: Study Learning juggling or other complex new skills prompts improvements in the brain's signaling network, a finding that could lead to new ways to treat people with diseases such as multiple sclerosis, say U.K. researchers. The researchers used MRI imaging technology to monitor the brains of healthy young adults who were given weekly juggling training sessions for six weeks and then practiced for 30 minutes a day. The jugglers showed a 5 percent increase in brain white matter compared with non-jugglers, BBC News reported. The Oxford University study appeared in the journal Nature Neuroscience. "MRI is an indirect way to measure brain structure and so we cannot be sure exactly what is changing when these people learn," said team leader Dr. Heidi Johansen-Berg, BBC News reported. "Future work should test whether these results reflect changes in the shape or number of nerve fibers, or growth of the insulating myelin sheath surrounding the fibers." "Of course, this doesn't mean that everyone should go out and start juggling to improve their brains," she added. "We chose juggling purely as a complex new skill for people to learn."Health Headlines - October 13
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