Friday, July 9, 2010

Scientists Discover HIV-Fighting Antibodies

BOSTON: Government scientists have identified two human antibodies they believe can prevent 90 percent of known HIV strains from infecting cells, the National Institutes of Health announced Thursday.

According to the agency, NIH scientists believe the two antibodies can be harnessed to create more potent HIV vaccines or better treatments for the condition.

"The discovery of these exceptionally broadly neutralizing antibodies to HIV and the structural analysis that explains how they work are exciting advances that will accelerate our efforts to find a preventive HIV vaccine for global use," said Anthony Fauci, director of the NIH's National Institute of Allergy and Infectious Diseases, which conducted the research.

The scientists identified the two antibodies as VRC01 and VRC02. Laboratory studies showed the antibodies could neutralize a larger number of HIV strains with greater efficiency than previously identified antibodies.

Details from the study were published Thursday in the online edition of the research journal Science.

Scientists from several other institutions also participated in the research study, including those from Beth Israel Deaconess Medical Center, Boston; Columbia University, New York; Harvard Medical School and Harvard School of Public Health, Boston; Rockefeller University, New York; and the University of Washington, Seattle.

Shares of two of the leading HIV-treatment makers, Bristol-Myers Squibb and Gilead Sciences, were down 1 percent in Thursday afternoon trading.

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Originally published by By Val Brickates Kennedy MarketWatch.

(c) 2010 Herald; Rock Hill, S.C.. Provided by ProQuest LLC. All rights Reserved.

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